Police said Salma Chadee was shot at her home on Saturday night while in the company of relatives and the wheelchair-bound man, who broke his legs in a car accident recently.
They said the man, who is also wanted in connection with the murder of another woman, Sherlene Mahangoo-Charles, and injury to her 14-year-old daughter, shot the woman several times following an argument.
So far 22 people have been killed here since the start of the year.